Study of Frozen Solutions of Nucleic Acid Nitrogen Bases by Means of Low Temperature Fast-atom Bombardment Mass Spectrometry

The electropolymerization of 2,5-di(2-(thienyl)pyrrole) (SNS) on a Pt electrode from ethanolic solution with LiClO4 or LiCl as electrolyte has been studied by cyclic voltammetry (CV) and chronoamperometry (CA). In both media, a quasi-reversible process has been indicated by CV, reversing the scan at low oxidation potentials. Under these conditions, reducible positive charges formed in both oxidized polymers are compensated by the entrance of anions from solution. Elemental analysis reveals that polymers generated at a low oxidation potential by CA contain a 21.03% (w/w) of ClO4- or a 9.56% (w/w) of Cl-. The poly(SNS) doped with Cl- presents higher proportion of reducible positive charges, higher polymerization charge and lower productivity. A much higher electrical conductivity, however, has been found for the poly(SNS) doped with ClO4-. Both polymers are soluble in DMSO, acetone and methanol. The dimer, trimer, tetramer and pentamer have been detected as soluble and neutral linear oligomers by mass spectrometry-fast atom bombardment. The analysis of polymers by infrared spectroscopy confirms the predominant formation of linear molecules with α-α linkages between monomeric units. A condensation mechanism involving one-electron oxidation of all electrogenerated linear and neutral polymeric chains is proposed to explain the SNS electropolymerization.

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Low-temperature oxidation of a gasoline surrogate: Experimental investigation in JSR and RCM using high-resolution mass spectrometry

Combustion and Flame ◽

10.1016/j.combustflame.2021.01.037 ◽

2021 ◽

Vol 228 ◽

pp. 128-141

Author(s):

Nesrine Belhadj ◽

Roland Benoit ◽

Philippe Dagaut ◽

Maxence Lailliau ◽

Bruno Moreau ◽

...

Keyword(s):

Mass Spectrometry ◽

Experimental Investigation ◽

High Resolution ◽

Low Temperature ◽

High Resolution Mass Spectrometry ◽

Low Temperature Oxidation ◽

Temperature Oxidation ◽

High Resolution Mass ◽

Resolution Mass

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A revised primary structure for neocarzinostatin based on fast atom bombardment and gas chromatographic-mass spectrometry.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)90583-1 ◽

1984 ◽

Vol 259 (17) ◽

pp. 10801-10806

Author(s):

B W Gibson ◽

W C Herlihy ◽

T S Samy ◽

K S Hahm ◽

H Maeda ◽

...

Keyword(s):

Mass Spectrometry ◽

Primary Structure ◽

Fast Atom Bombardment ◽

Chromatographic Mass

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Assignment of disulfide bonds in proteins by fast atom bombardment mass spectrometry.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)61533-9 ◽

1987 ◽

Vol 262 (6) ◽

pp. 2507-2513

Author(s):

R. Yazdanparast ◽

P.C. Andrews ◽

D.L. Smith ◽

J.E. Dixon

Keyword(s):

Mass Spectrometry ◽

Disulfide Bonds ◽

Fast Atom Bombardment

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Surface acoustic wave nebulization improves compound selectivity of low-temperature plasma ionization for mass spectrometry

Scientific Reports ◽

10.1038/s41598-021-82423-w ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Andreas Kiontke ◽

Mehrzad Roudini ◽

Susan Billig ◽

Amarghan Fakhfouri ◽

Andreas Winkler ◽

...

Keyword(s):

Mass Spectrometry ◽

Low Temperature ◽

Acoustic Wave ◽

Surface Acoustic Wave ◽

Ionization Mechanism ◽

Low Temperature Plasma ◽

Ambient Conditions ◽

Temperature Plasma ◽

Plasma Ionization ◽

Surface Acoustic Wave Nebulization

AbstractMass spectrometry coupled to low-temperature plasma ionization (LTPI) allows for immediate and easy analysis of compounds from the surface of a sample at ambient conditions. The efficiency of this process, however, strongly depends on the successful desorption of the analyte from the surface to the gas phase. Whilst conventional sample heating can improve analyte desorption, heating is not desirable with respect to the stability of thermally labile analytes. In this study using aromatic amines as model compounds, we demonstrate that (1) surface acoustic wave nebulization (SAWN) can significantly improve compound desorption for LTPI without heating the sample. Furthermore, (2) SAWN-assisted LTPI shows a response enhancement up to a factor of 8 for polar compounds such as aminophenols and phenylenediamines suggesting a paradigm shift in the ionization mechanism. Additional assets of the new technique demonstrated here are (3) a reduced analyte selectivity (the interquartile range of the response decreased by a factor of 7)—a significant benefit in non-targeted analysis of complex samples—and (4) the possibility for automated online monitoring using an autosampler. Finally, (5) the small size of the microfluidic SAWN-chip enables the implementation of the method into miniaturized, mobile LTPI probes.

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